Phlebotomy as a preventive measure for crocidolite-induced mesothelioma in male rats

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Phlebotomy as a preventive measure for crocidolite‐induced mesothelioma in male rats

Malignant mesothelioma (MM) is a rare but socially important neoplasm due to its association with asbestos exposure. Malignant mesothelioma is difficult to diagnose at an early stage, yet there are no particularly effective treatments available at the advanced stage, thus necessitating efficient strategies to prevent MM in individuals already exposed to asbestos. We previously showed that persi...

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Further Evidence for Fiber Width as a Determinant of Mesothelioma Induction and Threshold*Anthophyllite, Bolivian Crocidolite, and Cape Crocidolite

Crocidolite is a well-known causative agent for mesothelioma. However, studies have shown that the pathogenicity of the fiber from different mines varies considerably and it has been postulated the parameter that appears most likely to account for this variation is fiber width although this has never been formally confirmed. To date, crocidolite appears to be the only asbestos mineral for which...

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Preventive effect of Cynodon dactylon against ethylene glycol-induced nephrolithiasis in male rats

Objective: This study was carried out to investigate the preventive effects of hydroalcoholic extract of Cynodon dactylon(C.dactylon) roots on calcium oxalate calculi in rat. Materials and Methods: 24 Wistar rats were randomly divided into 4 groups: group A received tap drinking water while, Groups B, C, and D received 1% ethylene glycol daily for 28 days. Rats in groups C and D received ethan...

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Mesothelioma in an individual following exposure to crocidolite-containing gaskets as a teenager.

Mesothelioma is considered a signal tumor for asbestos exposure and typically occurs decades after first exposure to asbestos. Tissue analysis often indicates past exposure to mixed types of asbestos. This report describes the case of a 58-year-old man who developed mesothelioma after reported exposure to crocidolite from asbestos-containing gaskets beginning at age 16 during three summers duri...

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ژورنال

عنوان ژورنال: Cancer Science

سال: 2018

ISSN: 1347-9032

DOI: 10.1111/cas.13460